What if you'd held LXRX?
A $1,000 investment in Lexicon Pharmaceuticals, Inc. (LXRX) at the month-end close of 2000-04 would be worth $32.82 at the close of 2026-09 — -96.7% total return, dividends reinvested. The same $1,000 in the S&P 500, dividends reinvested, would be worth $8,565.
Your scenario
Result
If you'd bought $1,000 at the start of each year
Value of $1,000 invested on January 1 of each year, held to 2026-09, dividends included.
Every year, $1,000 from 2000
| Year | Value of $1,000 | Year return |
|---|---|---|
| 2000 | $1,000 | — |
| 2001 | $694 | -30.6% |
| 2002 | $285 | -59.0% |
| 2003 | $354 | +24.5% |
| 2004 | $467 | +31.7% |
| 2005 | $220 | -53.0% |
| 2006 | $217 | -1.1% |
| 2007 | $182 | -16.1% |
| 2008 | $84.21 | -53.8% |
| 2009 | $102 | +21.4% |
| 2010 | $86.62 | -15.3% |
| 2011 | $77.59 | -10.4% |
| 2012 | $133 | +71.3% |
| 2013 | $108 | -18.6% |
| 2014 | $54.74 | -49.4% |
| 2015 | $114 | +108.9% |
| 2016 | $119 | +3.9% |
| 2017 | $84.90 | -28.6% |
| 2018 | $57.06 | -32.8% |
| 2019 | $35.66 | -37.5% |
| 2020 | $29.39 | -17.6% |
| 2021 | $33.86 | +15.2% |
| 2022 | $16.41 | -51.5% |
| 2023 | $13.15 | -19.9% |
| 2024 | $6.36 | -51.6% |
| 2025 | $9.88 | +55.4% |
| 2026 | $19.25 | +94.8% |
Best and worst month-end to buy
The best single month-end close to have bought LXRX was 2025-03 ($0.46): $1,000 then is $4,870 today. The worst was 2000-06 ($241): $1,000 then is $9.31.
FAQ
What would $1,000 in LXRX be worth today?
A $1,000 investment in Lexicon Pharmaceuticals, Inc. (LXRX) at the start of 2000 would be worth about $32.82 today, a total return of -96.7%. Dividends are reinvested in these figures.
What were the best and worst years for LXRX?
Lexicon Pharmaceuticals, Inc. (LXRX)'s strongest calendar year since 2000 was 2015, a +108.9% return — $1,000 held through that year became about $2,089 by year-end. Its weakest year was 2002, at -59.0%.
Does the calculator include dividends and splits?
Yes where available. Prices are adjusted for both stock splits and reinvested dividends (total return), the same measure brokerages use.
How much would $100 per month in LXRX have grown?
Investing $100 at the end of every month since 2000-04 would have grown to about $14,813 on $31,800 invested.
Did LXRX beat the S&P 500?
Over the same period, $1,000 in the S&P 500 with dividends reinvested (the S&P 500 Total Return index) would be worth $8,565. LXRX trailed the S&P 500 by +99.6% in total return.
Is this investment advice?
No. Wall Street Regrets is an entertainment and education tool. Every number is a historical calculation, not a prediction, and past performance never guarantees future results.
Methodology
Lexicon Pharmaceuticals, Inc. (LXRX) historical total-return data from 2000-04 to 2026-09, reduced to month-end closes for the tables above.
Returns use adjusted close prices — adjusted for stock splits and reinvested dividends, the same convention used by major brokerages. End-of-day and live prices come from EODHD; parts of the deep historical series are carried over from Yahoo Finance data. A "year" scenario invests $1,000 at the prior December's month-end close and values it at the latest available month-end close. Non-USD amounts are converted at historical month-end exchange rates (EODHD): to USD on the buy date and back to your currency at the latest rate, so the return reflects the currency move as well as the asset.
Month-end resolution means intra-month extremes are not captured in tables; the calculator uses exact trading-day closes where daily data is available. Figures ignore taxes, fees, and the currency effects of non-USD listings. History is not a forecast. Wall Street Regrets is entertainment, not investment advice.
What if you'd held…
Data: adjusted close prices via EODHD and Yahoo Finance. As of 2026-09-02. Not financial advice.